Publication The promise of bispecific antibodies: Clinical applications and challenges.
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조회 539회 작성일 24-02-23 11:13
조회 539회 작성일 24-02-23 11:13
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| Journal | Cancer Treat Rev. |
|---|---|
| Name | Lim SM, Pyo KH, Soo RA, Cho BC. |
| Year | 2021 |
Abstract
The development of cancer therapies using monoclonal antibodies has been successful during the last 30 years. Recently much progress was achieved with technologies involving bispecific and multi-specific antibodies. Bispecific antibodies (BsAbs) are antibodies that bind two distinct epitopes, and a large number of potential clinical applications of BsAbs have been described. Here we review mechanism of action, clinical development and future challenges of BsAbs which could be a serve as a valuable arsenal in cancer patients.
Keywords: Bispecific antibodies; Cancer.
Copyright © 2021 Elsevier Ltd. All rights reserved.